Pharma Analysis & QC

Trust our HPLC Columns, Solvents, Reagents, Standards, Filtration products and LC-MS workflow at any stage of your method development and validation. Whether it is ADME/DMPK, Drug Product Formulation, API Stability, Impurity Profiling, Dissolution Testing or USP/EP Monograph testing, we have the expertise to help you feel better about your small molecule, peptide, protein, mAbs, ADCs, or excipient analysis.

Featured Articles


Sigma-Aldrich Technical Article

LC-UV-MS Method Development for Antibody Drug Conjugates Using a Non-Toxic ADC-Mimic

Antibody-drug conjugates (ADC) represent a rapidly emerging class of biotherapeutic molecules, which harness the specificity of monoclonal antibodies (mAb) to selectively deliver highly potent cytotoxic drugs. Like all biotherapeutics they require significant analytical characterization. A non-toxic ADC surrogate, or “ADC Mimic,” with highly similar physicochemical properties to commercial ADCs provides an excellent molecule to safely drive analytical method development . . .

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Supelco Reporter

Certified Reference Materials for 19F Quantitative NMR Ensuring Traceability to “The International System of Units” (SI)

In recent years quantitative NMR (qNMR) spectroscopy has become one of the most important tools for content determination of organic substances and quantitative evaluation of impurities. The implementation of qNMR for new application fields, e.g. metabolomics, environmental analysis and physiological pathway studies, brings along more complex molecules and systems, thus making the use of 1H-qNMR challenging. A smart workaround is possible through use of other NMR active nuclei, namely 31P and 19F. . .  

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Supelco Technical Article

3S Reagents for Volumetric Titration

Connect Your Lab
3S is an intelligent packaging solution protected with an originality seal. The cap provides information via Radio-frequency identification or RFID, enabling automated data transfer between the reagent and titration instrument. Intelligent communication for improved performance.

Titration on a new level—wet chemical analysis is made safer and more reliable by 3S Adapter Technology:

Safe chemical handling: minimized risk of contamination through contact-free reagent exchange

Smart connection of chemical consumables: communication between the 3S cap and instrument software via RFID . . .