Cell culture media and supplements

As your cell therapy progresses from preclinical studies towards manufacturing, you need a partner who can help meet your cell culture media and supplement needs. MilliporeSigma offers products validated for several different cell therapy applications and expansion formats, including single use bioreactors. When you work with us, you can count on:

  • Highest quality raw materials
  • Product traceability and safety
  • Lot-to-lot consistency
  • Upstream supply chain stability
  • Cell therapy compatibility and application testing

 Featured product highlight

Cell culture media is a critical component in the cell therapy manufacturing workflow. Ensuring suitability for cell therapy applications requires an assessment of the supply chain security and regulatory friendliness of the product formulation. Using a xeno-free (XF) formulation that lacks fetal bovine serum addresses these concerns, but the performance of these formulations varies considerably for mesenchymal stem cells. Stemline® XF MSC Medium supports superior expansion performance of MSCs in planar and microcarrier culture formats as compared to αMEM/hPL and other XF formulations.


bmMSCs show improved growth in Stemline XF MSC Medium in the Mobius® 3 L single-use bioreactor relative toαMEM/hPL or a serum-free competitor product (A) while maintaining hMSC surface marker expression (B).

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We are devoted to meeting all your cell therapy manufacturing needs. Our extensive stem cell expertise and manufacturing experience make us an ideal partner to advance and translate your work to cell therapy success. Connect with us today to discuss your specific application needs.