Boronic Acids and Derivatives

Browse Our Boronic Acids and Derivatives

The Suzuki-Miyaura cross-coupling reaction is a powerful method for the palladium catalyzed formation of carbon-carbon bonds and is widely used in several applications in organic synthesis. The reaction is mediated by a catalytic palladium complex that unites an activated species (e.g. organohalide) with a boronic acid derivative. One of the elegant features of this chemistry is that boronic acids, in general, are relatively non-toxic and air and moisture stable compounds.

Sigma-Aldrich is pleased to provide a wide range of boronic acid derivatives from the more classically utilized boronic acids, e.g. phenylboronic acid, and boronate esters, such as pinacol and diboron esters, to the more recently developed technologies such as potassium trifluoroborate salts and MIDA boronate esters. All of our boronic acid derivatives are offered as alkyl, alkenyl, aryl and heteroaryl derivatives.

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Learn more about Boronic Acids and Derivatives
Slow-Release of Unstable Boronic Acids from MIDA Boronates
Formation of Complex Boronic Acids from MIDA Boronates
Potassium Organotrifluoroborates
Organotrifluoroborates: Expanding Organoboron Chemistry
MIDA Boronates
Iterative Cross-Coupling with MIDA Boronates: towards a General Strategy for Small-Molecule Synthesis
Potassium Trifluoroborate Salts
Preparation of trans-(2-bromovinyl) MIDA Boronate and Vinyl MIDA Boronate from the Corresponding Silanes