New Products for Chemical Synthesis

Mass Spectrometry-Cleavable Crosslinkers
A suite of new sulfoxide-containing crosslinkers (909602,909610,909599,909688) are ideal tools for analysis of protein-protein interactions (PPIs). Each homobifunctional linker contains an amino acid-targeting reactive group, a spacer region, and two symmetrical C-S cleavable bonds that yield tagged peptides for unambiguous identification via collision-induced dissociation using tandem MS. Such linkers will find wide utility in the elucidation of PPIs, protein complex architecture, and structural dynamics.

FastWoRX Separation Technology
FastWoRX products are hydrophobic powders that absorb most organic compounds. With them, liquid-liquid extraction (LLE) for reaction workups can be replaced by a simple filtration or magnetic separation. Products are available for filtration (FASTWORX-S) or magnetic separation (FASTWORX-M).

Air-stable Ni Catalysis

Ni(COD)(DQ) (912794) is an air- and thermally stable Ni(0) precatalyst developed by the Engle lab at The Scripps Research Institute. This 18-electron complex has a unique stability profile allowing for easy reaction setup outside an inert atmosphere. Transformations such as the Suzuki-Miyaura coupling, borylation of aryl halides, and alkene hydroarylation have been demonstrated.

Synthetic Reagents

Product #

Image

Description

Add to Cart

904090 (6R,7aR)-3-amino-8,8-dimethyltetrahydro-4H-3a,6-methanobenzo[d]oxazol-2(3H)-one hydrochloride 95% New
915319 Aminosupersilane New
FASTWORX-M FastWoRX-M Magnetic Powder  New
FASTWORX-S FastWoRX-S Sorbent Powder New

Chemical Biology

Product #

Image

Description

Add to Cart

910554 (S,R,S)-AHPC-PEG6-butyl CO2H ≥95% New
911801 AHPC-C6-PEG1-C3-PEG1-butyl amine hydrochloride ≥90% New
909688 Alkyne-A-DSBSO crosslinker ≥95% New
906107 (9-Aminononyl)triphenylphosphonium bromide 90% New
909629 Azide-A-DSBSO crosslinker ≥95% New
913863 Biotin-AEEA-tyramide New
914134 5-(Biotinamido)pentylamine TFA Salt ≥95% New
914916 Biotin-SS-tyramide ≥95% New
913979 Biotin-Thalidomide ≥95% New
914711 8-Biotinylamido-3,6-dioxaoctanoic acid ≥95% New
914924 3-[2-N-(Biotinyl)aminoethyldithio]propanoic acid ≥95% New
914460 1-Biotinyl-3,6-dioxa-8-octaneamine hydrochloride ≥95% New
909610 BMSO crosslinker ≥95% New
911798 N-(4-Bromophenyl)-N-phenylacrylamide ≥95% New
911690 C5 Lenalidomide ≥95% New
911739 C5 Lenalidomide-PEG1-NH2 hydrochloride ≥95% New
911747 C5 Lenalidomide-PEG3-NH2 hydrochloride ≥95% New
911704 C5 Lenalidomine-C3-NH2 hydrochloride ≥95% New
911712 C5 Lenalidomine-C6-NH2 hydrochloride ≥95% New
911720 C5 Lenalidomine-C9-NH2 hydrochloride ≥95% New
909661 d0-DMDSSO crosslinker ≥95% New
916080 Diethyl-4-cyclohexyl-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate ≥95% New
913766 9,10-Dioxo-9,10-dihydrophenanthrene-3-carboxylic acid ≥95% New
914487 2-(Diphenylphosphanyl)benzamide ≥95% New
909602 DSSO crosslinker ≥95% New
914002 Fmoc-Asp(CSY)-OH ≥95% New
914592 Fmoc-Cystamine HCl ≥95% New
914231 4-(2-(Hex-5-ynamido)ethyl)benzenesulfonyl fluoride ≥95% New
913839 2-Methylnicotinic acid imidazolide New
913588 O-(2-Nitrobenzyl)-L-tyrosine hydrochloride ≥95% New
914010 4-Nitrophenyl (2-(vinyloxy)ethyl) carbonate ≥95% New
910066 6-(2-(2-(Oct-7-yn-1-yloxy)ethoxy)ethoxy)hexanoic acid ≥90% New
914584 Phenylalanine-4′-azobenzene HCl ≥95% New
914312 N3-TFBA-O2Oc ≥98% New
914746 Thiophosphoro alkyne dichloridate ≥95% New
914983 ThT-NE ≥95% New

Catalysis

Product #

Image

Description

Add to Cart

913456 (R)-AntPhos ≥97% New
913200 (R)-BIDIME ≥97% New
912719 (S)-BIDIME ≥97% New
910430 Grubbs Catalyst® M220 Umicore New
903647 1-Heptyl-2-norbornene ≥95% New
912727 (2R,3R)-iPr-BIDIME New
914789 iPr-NDI ≥95% New
912948 Ir[FCF3(CF3)ppy]2(dtbbpy)PF6 New
912794 Ni(COD)(DQ) ≥95% New
913154 1,10-Phenanthroline nickel (ll) dibromide New
916129 1,10-Phenanthroline nickel (ll) dichloride New
912468 (2S,3S)-iPr-BIDIME ≥95% New
915610 PrPPTNO ≥95% New
908894   Rhodium(III) oxide/Platinum(IV) oxide hydrate New
912646 tBuBrettPhos Pd G6 bromide New
910228 1,3,5,7-Tetramethyl-2,4,8-trioxo-6-(2-bromophenyl)-6-phosphaadamantane ≥95% New
914371 Tris(cis-2,6-dimethylpiperidinyl)-cyclopropenium perchlorate ≥95% New