Showing 1-30 of 374 results for "440140"
Xiangwei Zhao et al.
Biosensors & bioelectronics, 72, 268-274 (2015-05-20)
Novel transducers are needed for point of care testing (POCT) devices which aim at facile, sensitive and quick acquisition of health related information. Recent advances in optofluidics offer tremendous opportunities for biological/chemical analysis using extremely small sample volumes. This paper...
Johanna C van den Beukel et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 28(11), 4857-4867 (2014-08-03)
Brown adipose tissue (BAT) and brown-like cells in white adipose tissue (WAT) can dissipate energy through thermogenesis, a process mediated by uncoupling protein 1 (UCP1). We investigated whether stress hormones ACTH and corticosterone contribute to BAT activation and browning of...
C Potrich et al.
Biomedical microdevices, 14(6), 1103-1113 (2012-07-05)
Modern Lab-on-a-chip (LOC) platforms for genomic applications integrate several biological tasks in a single device. Combination of these processes into a single device minimizes sample loss and contamination problems as well as reducing analysis time and costs. Here we present...
Xiao Jiang et al.
Biomedical microdevices, 17(1), 20-20 (2015-02-06)
Growth of the MDA-MB-231 breast cancer cell line in microfluidic channels was inhibited when culture media was delivered to the channels via microbore Tygon® tubing. Culture media incubated within this tubing also inhibited growth of these cells in conventional 96-well...
Tim Bobrowski et al.
Biosensors & bioelectronics, 101, 84-89 (2017-10-20)
We present a transparent and flexible self-charging biosupercapacitor based on an optimised mediator- and membrane-free enzymatic glucose/oxygen biofuel cell. Indium tin oxide (ITO) nanoparticles were spray-coated on transparent conducting ITO supports resulting in a flocculent, porous and nanostructured electrode surface....
Kai Wang et al.
Carbohydrate polymers, 129, 92-100 (2015-06-09)
The molecular structure and gelatinization properties of starches from domesticated African rice (Oryza glaberrima) and its wild progenitor (Oryza barthii) are determined and comparison made with Asian domesticated rice (Oryza sativa), the commonest commercial rice. This suggests possible enzymatic processes...
Ismail M Meraz et al.
PloS one, 9(4), e94703-e94703 (2014-04-17)
Porous silicon (pSi) microparticles, in diverse sizes and shapes, can be functionalized to present pathogen-associated molecular patterns that activate dendritic cells. Intraperitoneal injection of MPL-adsorbed pSi microparticles, in contrast to free MPL, resulted in the induction of local inflammation, reflected...
Luciana Armada et al.
Journal of endodontics, 41(8), 1281-1287 (2015-05-10)
The receptor activator of nuclear factor kappa B (RANK)-RANK ligand (RANKL)-osteoprotegerin (OPG) system is important in osteoclastogenesis and may play a role in the development of apical periodontitis. This immunohistochemical study evaluated the distribution of the expression of these regulators...
Marta Kumorek et al.
PloS one, 10(5), e0125484-e0125484 (2015-05-07)
In a typical cell culture system, growth factors immobilized on the cell culture surfaces can serve as a reservoir of bio-signaling molecules, without the need to supplement them additionally into the culture medium. In this paper, we report on the...
Yuhong Liu et al.
Journal of chromatography. A, 1364, 64-73 (2014-09-04)
Methicillin resistant Staphylococcus aureus (MRSA) is a bacterium that is resistant to many antibiotics. Resistance to methicillin is related to production of penicillin binding protein 2a (PBP2a). The currently presented research involves the development of antibody-linked immunoaffinity solid phase microextraction...
Reginald Tran et al.
Biomicrofluidics, 8(4), 046501-046501 (2014-11-08)
Cell culture in microfluidic systems has primarily been conducted in devices comprised of polydimethylsiloxane (PDMS) or other elastomers. As polystyrene (PS) is the most characterized and commonly used substrate material for cell culture, microfluidic cell culture would ideally be conducted...
Minggui Wang et al.
Langmuir : the ACS journal of surfaces and colloids, 31(22), 6220-6228 (2015-05-23)
Yolk@shell nanostructures of Au@r-GO/TiO2 with mesoporous shells were prepared by a sol-gel coating process sequentially with GO and TiO2 on Au/SiO2 core/shell spheres, followed by calcination and template removal, where the silica interlayer acts as a template not only to...
Yuxiong Huang et al.
Water research, 80, 159-168 (2015-05-23)
Cadmium (Cd(2+)) and lead (Pb(2+)) are toxic to human beings and other organisms, and the U.S. Environmental Protection Agency (EPA) has classified both as probable human carcinogens. In this study, a regenerable magnetic ligand particle (Mag-Ligand) which includes a metal-binding...
Amelie Hailer et al.
Oncotarget, 5(12), 4144-4153 (2014-07-02)
Several studies have linked overexpression of the LIM and SH3 domain protein 1 (LASP1) to progression of breast, colon, liver, and bladder cancer. However, its expression pattern and role in human prostate cancer (PCa) remained largely undefined. Analysis of published...
Ángel Martínez et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 21(44), 15651-15666 (2015-09-12)
A novel nanosystem based on mesoporous silica nanoparticles covered with carbosilane dendrons grafted on the external surface of the nanoparticles is reported. This system is able to transport single-stranded oligonucleotide into cells, avoiding an electrostatic repulsion between the cell membrane...
S R Simon Ting et al.
Biomaterials, 34(17), 4377-4386 (2013-03-13)
Cerium oxide nanoparticles (nanoceria) are effective in scavenging intracellular reactive oxygen species (ROS). In this study nanoceria synthesized by flame spray pyrolysis (dXRD = 12 nm) were functionalised with heparin via an organosilane linker, 3-aminopropyltriethoxysilane. Nanoceria were functionalised with approximately...
Joana F Sacramento et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 70, 107-116 (2015-02-11)
Caffeine, a non-selective adenosine antagonist, has distinct effects on insulin sensitivity when applied acutely or chronically. Herein, we investigated the involvement of adenosine receptors on insulin resistance induced by single-dose caffeine administration. Additionally, the mechanism behind adenosine receptor-mediated caffeine effects...
Dang-Dang Li et al.
Cell cycle (Georgetown, Tex.), 14(21), 3461-3474 (2015-11-15)
Although Hmgn1 is involved in the regulation of gene expression and cellular differentiation, its physiological roles on the differentiation of uterine stromal cells during decidualization still remain unknown. Here we showed that Hmgn1 mRNA was highly expressed in the decidua...
Minh Hai Le et al.
Sensors (Basel, Switzerland), 15(5), 10686-10704 (2015-05-09)
Nanoporous SnO2 thin films were elaborated to serve as sensing electrodes for label-free DNA detection using electrochemical impedance spectroscopy (EIS). Films were deposited by an electrodeposition process (EDP). Then the non-Faradic EIS behaviour was thoroughly investigated during some different steps...
Ke Xu et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 25(19), 5014-5021 (2019-01-27)
CH3 NH3 PbBr3 perovskite quantum dots (PQDs) are synthesized by using four different linear alkyl phosphonic acids (PAs) in conjunction with (3-aminopropyl)triethoxysilane (APTES) as capping ligands. The resultant PQDs are characterized by means of XRD, TEM, Raman spectroscopy, FTIR spectroscopy...
Yunus Alapan et al.
Scientific reports, 4, 7173-7173 (2014-11-25)
We present a microfluidic approach that allows simultaneous interrogation of RBC properties in physiological flow conditions at a single cell level. With this method, we studied healthy hemoglobin A (HbA) and homozygous sickle hemoglobin (HbS) containing RBCs using whole blood...
S K Vashist et al.
The Analyst, 140(13), 4445-4452 (2015-05-13)
A rapid and highly-sensitive surface plasmon resonance (SPR)-based immunoassay (IA) has been developed and validated for detecting human C-reactive protein (CRP), a specific biomarker for inflammatory and metabolic disorders, and infections. The 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide hydrochloride (EDC)-activated protein A/G (Pr A/G) was...
Young-Kwan Kim et al.
Small (Weinheim an der Bergstrasse, Germany), 11(21), 2527-2535 (2015-01-30)
The paper reports a facile one-pot synthesis of core@shell nanoparticles (NPs) composed of Au core and graphene oxide nanocolloid (GON) shell. Unique properties of Au NPs and GON can be incorporated into a single nanohybrid structure to provide desirable functions...
Jiajia Xue et al.
ACS nano, 9(2), 1600-1612 (2015-01-15)
Guided tissue regeneration/guided bone regeneration membranes with sustained drug delivery were developed by electrospinning drug-loaded halloysite clay nanotubes doped into poly(caprolactone)/gelatin microfibers. Use of 20 wt % nanotube content in fiber membranes allowed for 25 wt % metronidazole drug loading...
Mohammad E Khosroshahi et al.
Lasers in medical science, 30(7), 1913-1922 (2015-07-04)
In this study, we report the apoptosis induction in HER2 overexpressed breast cancer cells using pulsed, continuous wave lasers and polyvinylpyrrolidone (PVP)-stabilized magneto-plasmonic nanoshells (PVP-MPNS) delivered by immunoliposomes. The immunoliposomes containing PVP-MPNS were fabricated and characterized. Heating efficiency of the...
Qiu-Ping Li et al.
Journal of colloid and interface science, 380(1), 67-74 (2012-06-15)
A series of ternary rare earth (Eu(3+), Tb(3+)) complexes are covalently coated to the 3-aminopropyltriethoxysilane functionalized multi-walled carbon nanotube (MWCNT) by a simple in situ sol-gel method by the bifunctional silylated monomer TTA-Si and TAA-Si (TTA-Si and TAA-Si are 3-(triethoxysilyl)propylisocyanate...
Rahul P Bagwe et al.
Langmuir : the ACS journal of surfaces and colloids, 22(9), 4357-4362 (2006-04-19)
In this article, a systematic study of the design and development of surface-modification schemes for silica nanoparticles is presented. The nanoparticle surface design involves an optimum balance of the use of inert and active surface functional groups to achieve minimal...
Zhen Zou et al.
Biomaterials, 58, 35-45 (2015-05-06)
The development of multifunctional nanocarrier with each unit functioning at the correct time and location is a challenge for clinical applications. With this in mind, a type of intelligent mesoporous silica nanocarrier (PGFMSN) is proposed for matrix metalloprotease 2 (MMP...
Joshua A Weinstein et al.
Cell, 178(1), 229-241 (2019-06-25)
Analyzing the spatial organization of molecules in cells and tissues is a cornerstone of biological research and clinical practice. However, despite enormous progress in molecular profiling of cellular constituents, spatially mapping them remains a disjointed and specialized machinery-intensive process, relying...
Jennifer Vandooren et al.
The Biochemical journal, 465(2), 259-270 (2014-11-02)
Gelatinase B/matrix metalloproteinase-9 (MMP-9) (EC cleaves many substrates and is produced by most cell types as a zymogen, proMMP-9, in complex with the tissue inhibitor of metalloproteinases-1 (TIMP-1). Natural proMMP-9 occurs as monomers, homomultimers and heterocomplexes, but our knowledge about...

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