Showing 1-30 of 278 results for "281778"
Shen-Hsing Hsu et al.
Scientific reports, 7(1), 8363-8363 (2017-08-23)
Proteins belonging to the toll-like receptor (TLR) family, particularly TLR2, are the major components of innate immunity against Leptospira infection. The ligands for TLR2 harbor several conserved patterns such as lipidation molecules, leucine-rich repeat (LRR) domains, TLR2 binding motifs, and...
Sasan Jalili-Firoozinezhad et al.
Nature biomedical engineering, 3(7), 520-531 (2019-05-16)
The diverse bacterial populations that comprise the commensal microbiome of the human intestine play a central role in health and disease. A method that sustains complex microbial communities in direct contact with living human intestinal cells and their overlying mucus...
Yen P Kong et al.
Biomaterials, 181, 280-292 (2018-08-11)
During normal development, the extracellular matrix (ECM) regulates cell fate mechanically and biochemically. However, the ECM's influence on lineage reprogramming, a process by which a cell's developmental cycle is reversed to attain a progenitor-like cell state followed by subsequent differentiation...
Xin-Chun Huang et al.
Acta biomaterialia, 23, 263-270 (2015-05-20)
Silica-based nanomaterials have demonstrated great potential in biomedical applications due to their chemical inertness. However, the degradability and endosomal trapping issues remain as rate-limiting barriers during their innovation. In this study, we provide a simple yet novel sol-gel approach to...
Arthur H Cheng et al.
Cell reports, 26(12), 3191-3202 (2019-03-21)
Clock neurons within the mammalian suprachiasmatic nuclei (SCN) encode circadian time using interlocked transcription-translation feedback loops (TTFLs) that drive rhythmic gene expression. However, the contributions of other transcription factors outside of the circadian TTFLs to the functionality of the SCN...
Elham Zakerzadeh et al.
Artificial cells, nanomedicine, and biotechnology, 45(8), 1509-1520 (2016-12-03)
Here a novel antibacterial nanocomposite was developed for combination cancer therapy. The synthesized nanocarrier was characterized by FTIR
Dong-Wook Lee et al.
Scientific reports, 5, 15931-15931 (2015-10-31)
The development of easier, cheaper, and more ecofriendly synthetic methods for mesoporous materials remains a challenging topic to commercialize them, and the transformation of waste glycerol, as a biodiesel byproduct, into something useful and salable is one of the pending...
Chia-Hui Chu et al.
International journal of molecular sciences, 20(7) (2019-03-31)
Nanoparticle-based imaging contrast agents have drawn tremendous attention especially in multi-modality imaging. In this study, we developed mesoporous silica nanoparticles (MSNs) for use as dual-modality contrast agents for computed tomography (CT) and near-infrared (NIR) optical imaging (OI). A microwave synthesis...
Mohammad Taleb et al.
Advanced healthcare materials, 8(18), e1900283-e1900283 (2019-08-06)
Tumor blood vessels have been reported to be abnormal in both structure and function compared with those in normal tissues, leading to a hostile microenvironment and inadequate antitumor drug delivery. Dopamine, a chemical messenger, is proven to inhibit angiogenesis and...
A R Ghiasvand et al.
The Analyst, 143(11), 2632-2640 (2018-05-15)
A low-cost and reliable cooling/heating-assisted microextraction (CHaME) instrument was designed and fabricated for use in different modes of microextraction methods. The CHaME setup is able to cool down the sorbent and simultaneously heat the sample in a wide temperature range....
Sarah Moitrier et al.
Soft matter, 15(4), 537-545 (2018-12-06)
We study the competition for space between two cell lines that differ only in the expression of the Ras oncogene. The two cell populations are initially separated and set to migrate antagonistically towards an in-between stripe of free substrate. After...
Tom Flossmann et al.
Cell reports, 26(12), 3173-3182 (2019-03-21)
Synchronized activity is a universal characteristic of immature neural circuits that is essential for their developmental refinement and strongly depends on GABAergic neurotransmission. A major subpopulation of GABA-releasing interneurons (INs) expresses somatostatin (SOM) and proved critical for rhythm generation in...
Fanyongjing Wang et al.
Sensors (Basel, Switzerland), 15(8), 18040-18060 (2015-07-28)
Whispering Gallery Mode (WGM) optical microresonator biosensors are a powerful tool for targeted detection of analytes at extremely low concentrations. However, in complex environments, non-specific adsorption can significantly reduce their signal to noise ratio, limiting their accuracy. To overcome this...
JinHyeong Lee et al.
Scientific reports, 8(1), 12078-12078 (2018-08-15)
We are proposed that a possible mechanism for Cr(VI) removal by functionalized mesoporous silica. Mesoporous silica was functionalized with (3-aminopropyl)trimethoxysilane (APTMS) using the post-synthesis grafting method. The synthesized materials were characterized using transmission electron microscopy (TEM), X-ray diffraction (XRD), N2...
Andisheh Motealleh et al.
Biofabrication, 11(3), 035022-035022 (2019-04-04)
In this study we describe the first example of 3D bioprinted triphasic chiral nanocomposite (NC) hydrogels/scaffolds to simulate the complex 3D architecture, nano/micro scale topography, and chiral nature of extracellular matrix. These multifunctional constructs are prepared using a 3D bioprinting...
Davide Rovati et al.
Nanomaterials (Basel, Switzerland), 9(9) (2019-09-12)
The adhesion and proliferation of bacteria on abiotic surfaces pose challenges in both health care and industrial applications. Gold nanostars (GNSs) monolayers grafted on glass have demonstrated to exert antibacterial action due to their photo-thermal features. Here, these GNS layers...
Mariano D Susman et al.
Nanoscale, 9(34), 12573-12589 (2017-08-19)
Oxidation and corrosion reactions have a major effect on the application of non-noble metals. Kinetic information and simple theoretical models are often insufficient for describing such processes in metals at the nanoscale, particularly in cases involving formation of internal voids...
J Gautier et al.
International journal of pharmaceutics, 423(1), 16-25 (2011-06-28)
One of the new strategies to improve cancer chemotherapy is based on new drug delivery systems, like the polyethylene glycol-coated superparamagnetic iron oxide nanoparticles (PEG-SPION, thereafter called PS). In this study, PS are loaded with doxorubicin (DOX) anticancer drug, using...
HaeYong Seok et al.
Journal of controlled release : official journal of the Controlled Release Society, 265, 66-74 (2017-04-25)
Intradermal DNA vaccination is a promising method of immunization that overcomes some practical drawbacks of conventional intramuscular vaccinations. However, it is difficult to deliver DNA vaccines to target cells in the skin and polyplexes. This study outlines the development of...
Ewa Moczko et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1124, 1-6 (2019-06-09)
Herein an approach to prepare molecularly imprinted polymer nanoparticles (nanoMIPs) with specific binding affinity for antibodies is reported. The process relied on the covalent immobilization of the template (whole immunoglobulin G (IgG), Fc domain of human IgG and peptide epitope)...
Mingwu Shen et al.
Nanotechnology, 23(10), 105601-105601 (2012-02-22)
We report a facile approach to synthesizing 3-aminopropyltrimethoxysilane (APTS)-coated magnetic iron oxide (Fe(3)O(4)@APTS) nanoparticles (NPs) with tunable surface functional groups for potential biomedical applications. The Fe(3)O(4) NPs with a mean diameter of 6.5 nm were synthesized by a hydrothermal route in...
Hongyun Niu et al.
Analytical chemistry, 81(24), 9913-9920 (2009-11-17)
In this study, octadecyl (C(18)) and aminopropyl group modified titanate nanotubes (C(18)/NH(2)-TNs) were prepared successfully with a silylation method by introducing octadecyltrimethoxysilane (ODS) and aminopropyltrimethoxysilane (APS) simultaneously to the surface of titanate nanotubes (TNs). The properties of the products were...
Wen Xu et al.
Mikrochimica acta, 186(10), 673-673 (2019-09-09)
Water-dispersed silicon quantum dots (SiQDs) with the quantum yield of 25% was prepared using aminopropyltrimethoxysilane as the silicon source and ascorbic acid (AA) as the reduction reagent. The SiQDs display blue fluorescence with excitation/emission peaks at 350 nm/440 nm. The synthesized SiQDs...
Yousef Nazari et al.
Environmental science and pollution research international, 26(24), 25359-25371 (2019-07-01)
In the present article, Fe3O4@TiO2 core/shell (FT) linked to graphene was fabricated by sol-gel technique as a photocatalyst and was employed for the solar degradation of cationic methylene blue (MB) in aqueous solution. The prepared core/shells were linked to graphene...
Li-Ching Huang et al.
Biomedical optics express, 9(5), 2142-2153 (2018-05-16)
Complete removal of a glioblastoma multiforme (GBM), a highly malignant brain tumor, is challenging due to its infiltrative characteristics. Therefore, utilizing imaging agents such as fluorophores to increase the contrast between GBM and normal cells can help neurosurgeons to locate...
Jing Neng et al.
Journal of agricultural and food chemistry, 66(22), 5707-5712 (2018-05-08)
A robust immunoassay based on surface-enhanced Raman scattering (SERS) has been developed to simultaneously detect trace quantities of multiple pathogenic antigens from West Nile virus, Rift Valley fever virus, and Yersinia pestis in fetal bovine serum. Antigens were detected by...
Jiangping Chen et al.
Sensors (Basel, Switzerland), 15(6), 12205-12217 (2015-05-29)
In this study, we developed a reflective localized surface plasmon resonance (LSPR) optical fiber sensor, based on silver nanoparticles (Ag NPs). To enhance the sensitivity of the LSPR optical sensor, two key parameters were optimized, the length of the sensing...
Guillaume Chantereau et al.
Carbohydrate polymers, 220, 71-78 (2019-06-15)
In this work, we report a convenient method of grafting non-leachable bioactive amine functions onto the surface of bacterial cellulose (BC) nanofibrils, via a simple silylation treatment in water. Two different silylation protocols, involving different solvents and post-treatments were envisaged...
Limmer, S.J. et al.
The Journal of Physical Chemistry B, 107, 13313-13313 (2003)
Hongjing Wang et al.
Chemistry, an Asian journal, 14(17), 3019-3024 (2019-07-30)
Tailoring the morphology and composition of platinum-based electrocatalysts is of significant importance for the development of highly efficient direct methanol fuel cells. Herein, we report a dual-templating method for the design of hollow PtPd nanorods with mesoporous shells (mPtPd HNRs). We...

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