Ana M S Cardoso et al.
Human molecular genetics, 28(16), 2738-2751 (2019-05-16)
Glioblastoma (GB) is the most aggressive and common form of primary brain tumor, characterized by fast proliferation, high invasion, and resistance to current standard treatment. The average survival rate post-diagnosis is only of 14.6 months, despite the aggressive standard post-surgery treatment...
Cindy C Shu et al.
Arthritis & rheumatology (Hoboken, N.J.), 68(4), 868-879 (2015-12-05)
To investigate the role of the heparan sulfate (HS) proteoglycan perlecan (HSPG-2) in regulating fibroblast growth factor (FGF) activity, bone and joint growth, and the onset and progression of posttraumatic osteoarthritis (OA) in a mouse gene-knockout model. Maturational changes were...
Multi-Tissue Acceleration of the Mitochondrial Phosphoenolpyruvate Cycle Improves Whole-Body Metabolic Health.
Abulizi, et al.
Cell Metabolism, 32, 751-766 (2021)
Lingling Lu et al.
Acta histochemica, 121(6), 695-703 (2019-06-27)
Renal fibrosis is a common mechanism that leads to all kidney diseases and Epithelial-mesenchymal transition (EMT) is considered as one of the potential mechanisms of renal fibrosis. Inhibitor of growth 4 (ING4) was reported to involve in several diseases; especially...
Ayako Sasaki et al.
Human cell, 29(1), 37-45 (2015-11-11)
Of two stereoisomers of glucose, only D- and not L-glucose is abundantly found in nature, being utilized as an essential fuel by most organisms. The uptake of D-glucose into mammalian cells occurs through glucose transporters such as GLUTs, and this...