PVP40

Sigma-Aldrich

Polyvinylpyrrolidone

average mol wt 40,000

Synonym(s):
PVP, Povidone, Polyvidone
Linear Formula:
(C6H9NO)n
CAS Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.25

form

powder

Quality Level

mol wt

average mol wt 40,000

viscosity number

29-32(lit.)

Featured Industry

Agriculture

InChI

1S/C6H9NO/c1-2-7-5-3-4-6(7)8/h2H,1,3-5H2

InChI key

WHNWPMSKXPGLAX-UHFFFAOYSA-N

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General description

Polyvinylpyrrolidone (PVP) can form complexes with phenolics and alkaloids. The complex formation allows removal of phenolics and alkaloids from plant samples, thereby inhibiting any modification of proteins by them and any hindrance they may cause in spectrophotometric determinations of protein content. PVP might also enhances the stability of enzymes.

Application

Polyvinylpyrrolidone has been used in the purification of glutamine synthetases from plant samples. It has been used to block the PVDF (polyvinylidene difluoride) membrane and to avoid nonspecific binding.

Packaging

50, 100, 500 g in poly bottle
1 kg in poly bottle
5 kg in poly drum

Other Notes

Polyvinylpyrrolidone is a component of Denhardt′s Solution and is included at a concentration of 1% (w/v) in the standard 50X stock solution.

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Angiotensin II inhibits insulin signaling in aortic smooth muscle cells at multiple levels. A potential role for serine phosphorylation in insulin/angiotensin II crosstalk.
Folli F et al.
The Journal of Clinical Investigation, 100, 2158-2158 (1997)
Glutamine Synthetases of Higher Plants : Evidence for a Specific Isoform Content Related to Their Possible Physiological Role and Their Compartmentation within the Leaf.
McNally SF et al.
Plant Physiology, 72, 22-22 (1983)
Quantification of the Antioxidant Activity in Salt-Stressed Tissues.
Maksimovic JJD and Zivanovic BD
Plant Salt Tolerance: Methods and Protocols, 237-237 (2012)
Andreas U Müller et al.
Nature communications, 10(1), 4653-4653 (2019-10-13)
In mycobacteria, transcriptional activator PafBC is responsible for upregulating the majority of genes induced by DNA damage. Understanding the mechanism of PafBC activation is impeded by a lack of structural information on this transcription factor that contains a widespread, but...
Structural analysis of N- and O-glycans released from glycoproteins.
Jensen PH et al.
Nature Protocols, 7, 1299-1299 (2012)
Protocols
An introduction to both Northern and Southern blotting, popular methods for the transfer of macromolecules to membranous support. This article also offers a Southern blot protocol and a northern blot protocol.
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