ABS459

Sigma-Aldrich

Anti-USP10 Antibody

from rabbit, purified by affinity chromatography

Synonym(s):
Ubiquitin carboxyl-terminal hydrolase 10, Deubiquitinating enzyme 10, Ubiquitin thioesterase 10, Ubiquitin-specific-processing protease 10, UPS10
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

application(s)

immunocytochemistry: suitable
western blot: suitable

UniProt accession no.

shipped in

wet ice

General description

Ubiquitin carboxyl-terminal hydrolase 10 (USP10), also known as Ubiquitin-specific-processing protease 10, belongs to the peptidase C19 family and functions to catalyze the cleavage of ubiquitin from ubiquitin-conjugated protein substrates such as p53/TP53, SNX3 and CFTR. USP10 is widely expressed and is down-regulated in renal cell carcinomas.

Immunogen

KLH-conjugated linear peptide corresponding to human USP10.

Application

Research Category
Signaling
Immunocytochemistry Analysis: 20 µg/mL from a representative lot detected USP10 in Jurkat cells.
Research Sub Category
Developmental Signaling
Anti-USP10 Antibody is a highly specific rabbit polyclonal antibody, that targets Ubiquitin carboxyl-terminal hydrolase 10 & has been tested in western blotting & ICC.

Quality

Evaluated by Western Blotting in Jurkat cell lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected USP10 in 15 µg of Jurkat cell lysate.

Target description

~122 kDa observed. Uniprot describes 3 isoforms at ~~87 kDa, ~88 kDa, and ~93 kDa

Physical form

Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS with 0.1% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
Jurkat cell lysate

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

WGK Germany

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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