440183

Sigma-Aldrich

(3-Chloropropyl)trimethoxysilane

≥97%

Synonym(s):
δ-Chloropropyltrimethoxysilane, (γ-Chloropropyl)trimethoxysilane, (3-Chloropropyl)trimethoxysilane, 3-(Trimethoxysilyl)propyl chloride
Linear Formula:
Cl(CH2)3Si(OCH3)3
CAS Number:
Molecular Weight:
198.72
Beilstein/REAXYS Number:
969627
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.23
Pricing and availability is not currently available.

Quality Level

assay

≥97%

form

liquid

refractive index

n20/D 1.419 (lit.)

bp

195 °C/750 mmHg (lit.)

density

1.09 g/mL at 25 °C (lit.)

SMILES string

CO[Si](CCCCl)(OC)OC

InChI

1S/C6H15ClO3Si/c1-8-11(9-2,10-3)6-4-5-7/h4-6H2,1-3H3

InChI key

OXYZDRAJMHGSMW-UHFFFAOYSA-N

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General description

(3-Chloropropyl)trimethoxysilane (CPTMS) is an organo-silane which forms a self-assembled monolayer (SAMs) that facilitates the surface modification of different bio-and nano- materials.

Application

(3-Chloropropyl)trimethoxysilane may be used in the synthesis of octakis(3-chloropropyl)octasilsesquioxane.{35}
CPTMS can be used to silanize a variety of nanoparticles like carbon nanotubes (CNT) and silica nanoparticles (SiO2) for different applications like development for molecularly imprinted polymers for protein detection and fabrication of mesoporous silica(organic-inorganic hybrid). It may be used to functionalize silica-iron oxide nanoparticles which can be used as catalysts for the synthesis of pyrano(3,2−c:5,6−c′)dichromene-6,8-dione derivatives.

Packaging

1 L in Sure/Seal™
100 mL in Sure/Seal™

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

UN 1993C 3 / PGIII

WGK Germany

WGK 1

Flash Point(F)

161.1 °F - closed cup

Flash Point(C)

71.7 °C - closed cup

Grafting of molecularly imprinted polymers on iniferter-modified carbon nanotube.
Lee HY and Kim BS
Biosensors And Bioelectronics, 25(3), 587-591 (2009)
Guifang Wang et al.
Nanomaterials (Basel, Switzerland), 9(2) (2019-01-30)
In the present work, we describe a facile and general method of fabricating fluorescent inorganic nanoparticles with diverse shapes for cell imaging application. The hematite (α-Fe₂O₃) nanoparticles (HNPs) with three different shapes (i.e., spindle shape, ellipsoidal shape and quasi-spherical shape)...
Relation between the wetting effect and the adsorbed amount of water-soluble polymers or proteins at various interfaces.
Pandey LM and Pattanayek SK
Journal of Chemical and Engineering Data, 58(12), 3440-3446 (2013)
One-pot synthesis and modification of silica nanoparticles with 3-chloropropyl-trimethoxysilane assisted by microwave irradiation.
De Conto JF, et al.
Chemical Engineering Communications, 205(4), 533-537 (2018)
DABCO-modified super-paramagnetic nanoparticles as an efficient and water-compatible catalyst for the synthesis of pyrano (3, 2-c: 5, 6-c') dichromene-6, 8-dione derivatives under mild reaction conditions.
Heydari Z, et al.
Applied Organometallic Chemistry, 205(4), e4561-e4561 (2018)

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