APTS, APTES, 3-Triethoxysilylpropylamine
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Quality Level






217 °C/760 mmHg (lit.)


0.946 g/mL at 25 °C (lit.)

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InChI key


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General description

(3-Aminopropyl)tiethoxysilane (APTES) is used as an amino-silane which is mainly used as a dispersant. APTES attaches an amino group to the functional silane for bio-conjugation.


Forms aminopropyl derivative of glass, an adsorbent for affinity chromatography. Used to prepare positively charged slides suitable for use with various immunohistochemical and in situ hybridization procedures. Recently (3-Aminopropyl)triethoxysilane has been used to prepare dye-doped silica nanoparticles with minimal aggregation and minimal nonspecific binding with biomolecules.
Used in a preparation of a series of tenary composite films of polyimide/SiO/polydiphenylsiloxane with good optical transparency.
Self-assembled monolayer (SAM) of APTES can be used to improve the adhesion of graphene flakes and SiO2 to enable better contact with the metal electrodes. These electrodes may be used as electro-responsive tools for bio-sensing applications. It can be used to functionalize silane diazirine for fiber optic biosensor application. Hollow microcarriers (HMCs) can be surface modified with APTES which may be used for regenerative medicines and recombinant cells in biopharmaceutical industries.


100, 500 mL in Sure/Seal™


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Hazard Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves


UN 2735PSN1 8 / PGII

WGK Germany


Flash Point(F)

199.4 °F - closed cup

Flash Point(C)

93 °C - closed cup

  1. How should Product 440140, APTES (3-Aminopropyl)triethoxysilane) be stored?

    We would recommend storing this product in accordance with our MSDS, which recommends storing at room temperature and under inert gas since this product is moisture sensitive.

  2. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

Photoinducible silane diazirine as an effective crosslinker in the construction of a chemiluminescent immunosensor targeting a model E. coli analyte.
Ye Kehan, et al
Sensors and Actuators B, Chemical, 256(1), 234-242 (2018)
Functionalisation of Detonation Nanodiamond for Monodispersed, Soluble DNA-Nanodiamond Conjugates Using Mixed Silane Bead-Assisted Sonication Disintegration.
Edgington, et al.
Scientific Reports, 8(1), 728-728 (2018)
Polymer International, 55, 1277-1277 (2006)
Platinum nanoparticles homogenously decorating multilayered reduced graphene oxide for electrical nanobiosensor applications.
Proa-Coronado, et al.
Thin Solid Films, 658(1), 54-60 (2018)
Hollow microcarriers for large-scale expansion of anchorage-dependent cells in a stirred bioreactor.
YekrangSafakar, et al.
Biotechnology and Bioengineering, 115(7), 1717-1728 (2018)
Professor Aran (Claremont University, USA) thoroughly discusses the engineering of graphene based materials through careful functionalization of graphene oxide, a solution processable form of graphene.
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