134821

Sigma-Aldrich

Boron trifluoride-methanol solution

50% w/w in methanol

Linear Formula:
BF3 · MeOH
CAS Number:
Molecular Weight:
99.85
Beilstein/REAXYS Number:
3611499
MDL number:
PubChem Substance ID:

Quality Level

vapor pressure

19.5 mmHg ( 20 °C)

assay

49-53% (by NaOH, titration)

form

liquid

autoignition temp.

788 °F

reaction suitability

core: boron
reagent type: Lewis acid
reagent type: catalyst

concentration

50% w/w in methanol

application(s)

gas chromatography (GC): suitable

bp

59 °C/4 mmHg

density

1.203 g/mL at 25 °C

storage temp.

2-8°C

SMILES string

CO.FB(F)F

InChI

1S/CH4O.BF3/c1-2;2-1(3)4/h2H,1H3;

InChI key

JBXYCUKPDAAYAS-UHFFFAOYSA-N

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Related Categories

Application

Reagent for the GC analysis of ritalinic acid. Alternative to Cl2CHCO2H for synthesis of purine rich oligomers.
Lewis acid used in the preparation of geminal bis-peroxides from ketals and enol ethers with t-butyl hydroperoxide. Reagent used for the mild deacetylation of amines.

Packaging

1 L in glass bottle
4×25 mL in Sure/Seal™
50, 250 mL in glass bottle
The 25 mL Sure/Seal bottle is recommended as a single-use bottle. Repeated punctures will likely result in decreased performance of product.

Legal Information

Sure/Seal is a trademark of Sigma-Aldrich Co. LLC

Signal Word

Danger

Target Organs

Eyes, Kidney, Respiratory system

Supp Hazards

EUH014

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

UN 2920 3(8) / PGI

WGK Germany

WGK 2

Flash Point(F)

49.5 °F

Flash Point(C)

9.7 °C

Synthesis, 2215-2215 (2005)
Boron trifluoride-methanol complex as a non-depurinating detritylating agent in DNA synthesis.
M J Mitchell et al.
Nucleic acids research, 18(17), 5321-5321 (1990-09-11)
Tetrahedron Letters, 44, 2301-2301 (2003)
T Vu-Duc et al.
Journal of pharmaceutical and biomedical analysis, 10(2-3), 187-191 (1992-02-01)
Ritalinic acid (RITA), the major metabolite of methylphenidate (Ritaline) is extracted with a solid-phase C8 column. Following elution, methylation of the carboxylic group is performed with boron trifluoride-methanol as a reagent. The methyl ester of RITA which structurally corresponds to...
C Hue-Beauvais et al.
Journal of animal science, 93(4), 1641-1655 (2015-05-29)
Alterations to the metabolic endocrine environment during early life are crucial to mammary gland development. Among these environmental parameters, the initial nutritional event after birth is the consumption of milk, which represents the first maternal support provided to mammalian newborns....

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